Essays about: "Embryonic development"

Showing result 11 - 15 of 48 essays containing the words Embryonic development.

  1. 11. Significant increase in liver and heart mass found in post hatching red junglefowls (Gallus gallus).

    University essay from Linköpings universitet/Biologi

    Author : Frederik Pedersen; [2021]
    Keywords : Red Junglefowl; Gallus Gallus; Embryonic development; Hatchlings; Heart; Liver; Increase in mass;

    Abstract : Significant heart and liver increase in hatching and neonates has been found evident in multiple different species such as the emu, Peking Duck, and pigs. The relative mechanism behind heart growth could be tied to closing of the ductus arteriosus, however there is still a debate whether it’s significant impact in avian species. READ MORE

  2. 12. Development of a high-throughput platform for generation and early screening of high producing stable cell lines

    University essay from KTH/Proteinvetenskap

    Author : Jonathan Karlsson Persson; [2021]
    Keywords : CHO-K1; HEK293; CellCelector™; High-throughput screening; Protein A beads; Secondary antibody; CHO-K1; HEK293; CellCelector™; Högkapacitets-screening; Protein A-kulor; Sekundär antikropp;

    Abstract : Produktionen av rekombinanta biofarmaceutiska läkemedel, exempelvis monoklonala antikroppar, är en oumbärlig men ansträngande process. Under 2019 var sju av de tio mest sålda läkemedlen globalt baserade på rekombinant producerade monoklonala antikroppar. READ MORE

  3. 13. Optimizing signal peptides for expression of recombinant antibodies in HEK293 cells

    University essay from Linköpings universitet/Institutionen för fysik, kemi och biologi

    Author : Gustav Myhrinder; [2020]
    Keywords : Signal peptide; antibody; mammalian cell; HEK293; secretory pathway;

    Abstract : Monoclonal antibodies are well-established as a therapeutic in the biopharmaceutical market, targeting a variety of diseases and with 79 approved products by the United States Food and Drug Administration in December 2019. Therapeutic monoclonal antibodies are commonly produced as recombinant proteins in mammalian cell lines, due to their capacity of post-translational modifications, most notably glycosylation. READ MORE

  4. 14. Assessment of embryotoxicity of the antiandrogenic drugs flutamide and bicalutamide in zebrafish (Danio rerio)

    University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Author : Josefin Holmlund; [2020]
    Keywords : Antiandrogens; Androgen receptor inhibitors; Bicalutamide; Flutamide; Ecotoxicology; Environmental toxicity; Embryonic toxicity; Embryotoxicity; Zebrafish;

    Abstract : Introduction: Prostate cancer is the most common type of cancer in Sweden and is often treated using antiandrogenic drug therapy. Two substances belonging to this class of pharmaceuticals are bicalutamide and flutamide. After excretion from the human body, the drug molecules enter the wastewater treatment plant (WWTP). READ MORE

  5. 15. Effekten av PCB126 in vitro på tidig embryonalutveckling hos nötkreatur

    University essay from SLU/Dept. of Clinical Sciences

    Author : Erik Oscar Eriksson; [2020]
    Keywords : nötkreatur; bovin; embryoutveckling; in vitro; IVF; IVP; IVM; PCB; PCB 126; polyklorerade bifenyler;

    Abstract : Polyklorerade bifenyler (PCB) är industrikemikalier som började framställas i stora mängder under 1930-talet. Kommersiellt har PCB varit tillgängligt som komplexa kemiska blandningar i bland annat bekämpningsmedel, färg, plaster och olika elektriska komponenter. PCB är en grupp av över 200 dioxin- eller icke dioxinlika klorerade kolväten. READ MORE