Essays about: "Gene networks"

Showing result 26 - 30 of 52 essays containing the words Gene networks.

  1. 26. Identification of personalized multi-omic disease modules in asthma

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : David Martínez Enguita; [2018]
    Keywords : modules; asthma; personalized; systems biology; molecular biology; transcriptomics; genomics; networks; disease; biomarker; microarray; individualized; endotype; phenotype;

    Abstract : Asthma is a respiratory syndrome associated with airflow limitation, bronchial hyperresponsiveness and inflammation of the airways in the lungs. Despite the ongoing research efforts, the outstanding heterogeneity displayed by the multiple forms in which this condition presents often hampers the attempts to determine and classify the phenotypic and endotypic biological structures at play, even when considering a limited assembly of asthmatic subjects. READ MORE

  2. 27. Identifying Cell Reprogramming Roadblocks by Modelling Induced Pluripotency with Boolean Networks and Dynamical Systems

    University essay from Lunds universitet/Institutionen för astronomi och teoretisk fysik - Genomgår omorganisation; Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation

    Author : Johannes Isaksson; [2018]
    Keywords : Stem cells; pluripotency; pluripotent; reprogramming; iPS; induced pluripotency; Boolean; dynamical systems; network.; Medicine and Health Sciences;

    Abstract : The generation of induced pluripotent stem (iPS) cells from differentiated cells is a process of great scientific interest due to the medical potential of such cells. This process (called 'reprogramming' of cells) is however notoriously inefficient and still not very well understood. READ MORE

  3. 28. Robust Community Predictions of Hubs in Gene Regulatory Networks

    University essay from Linköpings universitet/Bioinformatik

    Author : Julia Åkesson; [2018]
    Keywords : Biological systems; Biological networks; Network inference; Gene regulatory networks; Hubs; Master regulators; Community predictions; Bioinformatics;

    Abstract : Many diseases, such as cardiovascular diseases, cancer and diabetes, originate from several malfunctions in biological systems. The human body is regulated by a wide range of biological systems, composed of biological entities interacting in complex networks, responsible for carrying out specific functions. READ MORE

  4. 29. Influence of probiotic treatment on allergy methylomics : Gene network analysis of epigenetic methylation patterns in CD4+ T cells from newborns treated with Lactobacillus reuteri

    University essay from Linköpings universitet/Bioinformatik

    Author : Simon Söderholm; [2018]
    Keywords : allergy; epigenetics; methylation; probiotics; bioinformatics; CD4 T cells; Lactobacillus reuteri; PPI-networks;

    Abstract : The composition and diversity of the gastrointestinal microbiota and its interaction with human cells have been frequently associated with immune system functions and disease development, including autoimmunity and allergy. This is believed to be mediated in part through epigenetic modifications, mainly as DNA methylation. READ MORE

  5. 30. The Function of FoxB During Limb Development and Axis Formation in the Spider Parasteatoda tepidariorum

    University essay from Uppsala universitet/Institutionen för geovetenskaper

    Author : Miriam Heingård; [2017]
    Keywords : spider; RNA interference; FoxB; ventral patterning; appendage; Drosophila; spindel; RNA interferens; FoxB; ventral; lemmar; Drosophila;

    Abstract : Arthropods are the most diverse and speciose group of animals on the planet. A key factor in their success is the adaptation of various appendages to new functions and environments, resulting in radically different morphologies. To understand this diversity, it is important to study the underlying genetic mechanisms. READ MORE