Essays about: "SCN1A"

Found 2 essays containing the word SCN1A.

  1. 1. Generation of induced pluripotent stem cells (iPSCs) lines deficient for genes associated with neurodevelopmental diseases using CRISPR/Cas9 technology

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Claudia De Guidi; [2021]
    Keywords : ;

    Abstract : Induced pluripotent stem cells (iPSCs) can self-renew and differentiate into many other cell types. IPSCs are derived from somatic cells, and upon reprogramming, they share an expression profile similar to embryonic stem cells (ESCs). READ MORE

  3. 2. The modeling of drug-induced changes in ion channel kinetics and firing properties in fast-spiking interneurons: a computational study

    University essay from Lunds universitet/Avdelningen för Biomedicinsk teknik

    Author : Alexander Cahlin; [2018]
    Keywords : Modeling; Hodgkin-Huxley; Nav1.1; VGSC; SCN1A; interneurons; AA43279; 3-amino-5- 4-methoxyphenyl thiophene-2-carboxamide; electrophysiology.; Technology and Engineering;

    Abstract : Interneurons have been found to be important for normal cognitive function. Impairments to their growth or signaling have been indicated to be involved in the development of schizophrenia, autism and epilepsy. READ MORE