Essays about: "Sequence alignment"

Showing result 1 - 5 of 32 essays containing the words Sequence alignment.

  1. 1. Prediction of multiple conformational states of membrane proteins

    University essay from Linköpings universitet/Bioinformatik

    Author : Tobias Thorén; [2024]
    Keywords : Bioinformatics; Protein prediction; AlphaFold;

    Abstract : Predicting protein structures has long been an area of active research in the field ofbioinformatics. Great strides have recently been made in this area by googles DeepMindteam. They developed an AI called AlphaFold which is able to make the most accuratepredictions of protein structures as of date. READ MORE

  3. 2. Determining Protein Conformational Ensembles by Combining Machine Learning and SAXS

    University essay from KTH/Tillämpad fysik

    Author : Samuel Eriksson Lidbrink; [2023]
    Keywords : AlphaFold; AlphaFold2; SAXS; protein conformational ensembles; machine learning; protein conformations; reweighting; SAXS; AlphaFold; AlphaFold2; proteinkonformationsensembler; maskininlärning; proteinkonformationer; omviktning;

    Abstract : In structural biology, immense effort has been put into discovering functionally relevant atomic resolution protein structures. Still, most experimental, computational and machine learning-based methods alone struggle to capture all the functionally relevant states of many proteins without very involved and system-specific techniques. READ MORE

  4. 3. Predicting Protein Stability with Machine Learning

    University essay from Lunds universitet/Biofysikalisk kemi

    Author : Lucas Carlsson; [2023]
    Keywords : Protein Stability; Biophysical Chemistry; Thermodynamics; Machine Learning; Deep Learning; Protein Language Model; Biochemistry; Multiple Sequence Alignment; Bioinformatics; Biology and Life Sciences;

    Abstract : Protein stability is a property of high importance and is of interest in a variety of fields. It determines if a protein has its native fold and can be of influence in certain diseases such as Parkinson's and Alzheimer's disease. READ MORE

  5. 4. Co-evolutional anaylsis of the Na+,K+-ATPase’s β-subunit dimerization

    University essay from KTH/Tillämpad fysik

    Author : Sebastian Bauer; [2023]
    Keywords : Na ; K -ATPase NKA ; Co-evolution; Dimerization; Direct coupling analysis DCA ; Molecular dynamic MD simulation; Contact filtering; Mapping; Na ; K -ATPas NKA ; Samevolution; Dimerisering; Direkt kopplingsanalys DKA ; Molekylär dynamisk MD simulering; Kontaktfiltrering; Kartläggning;

    Abstract : Does the active membrane transporter, Na+,K+-ATPase dimerize? If it does, whatis the functional benefit? Does it increase or decrease the turnover rate? Theseare still unanswered questions and current research topics. Previous studies havedemonstrated dimerizations in closely related proteins of the P-type ATPase family. READ MORE

  6. 5. Implementation of an Irregular Packaging Algorithm for Multi-Container

    University essay from Uppsala universitet/Industriell teknik

    Author : Azad Fakhir Salih; [2023]
    Keywords : irregular packaging problem; genetic algorithm; bottom-left placement; polygon-based geometric representation; proximity-based strategies;

    Abstract : This study introduces an innovative approach to address a complex, real-world packing problem experienced at Emerson Rosemount Tank Radar. The objectives of the study are manifold: primarily, the optimization of packing efficiency within specified geometric and box constraints, and secondarily, the fulfillment of specific packing objectives. READ MORE