Essays about: "AlphaFold"
Found 5 essays containing the word AlphaFold.
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1. Prediction of multiple conformational states of membrane proteins
University essay from Linköpings universitet/BioinformatikAbstract : Predicting protein structures has long been an area of active research in the field ofbioinformatics. Great strides have recently been made in this area by googles DeepMindteam. They developed an AI called AlphaFold which is able to make the most accuratepredictions of protein structures as of date. READ MORE
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2. Determining Protein Conformational Ensembles by Combining Machine Learning and SAXS
University essay from KTH/Tillämpad fysikAbstract : In structural biology, immense effort has been put into discovering functionally relevant atomic resolution protein structures. Still, most experimental, computational and machine learning-based methods alone struggle to capture all the functionally relevant states of many proteins without very involved and system-specific techniques. READ MORE
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3. Modelling Large Protein Complexes
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : AlphaFold [Jumper et al., 2021, Evans et al., 2022] is a deep learning-based method that can accurately predict the structure of single- and multiple-chain proteins. However, its accuracy decreases with an increasing number of chains, and GPU memory limits the size of protein complexes that can be predicted. READ MORE
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4. Modulation of a model ligand-gated ion channel by amphetamine derivatives
University essay from Uppsala universitet/StrukturbiologiAbstract : Pentameric ligand-gated ion channels are critical mediators of electrochemical signal transduction in neurons and other excitable cells, causing them to be important targets of psychoactive drugs. Structural data for these complex proteins are limited, particularly among eukaryotic family members and for the functionally critical open state. READ MORE
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5. Assignment of heteronuclear methyl-NMR spectrum of the 44 kDa protein MALT1 Casp-IgL3
University essay from Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisationAbstract : Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) plays an important role in the immune pathway that controls the activation and proliferation of B and T cells. Dysregularization of this pathway leads to the development of highly aggressive lymphomas. READ MORE
