Essays about: "biological sequence"

Showing result 1 - 5 of 40 essays containing the words biological sequence.

  1. 1. Effects of phosphorylation on the ADP-ribosylation activity of PARP16

    University essay from Lunds universitet/Kemiska institutionen

    Author : Virginia Martín Cristóbal; [2023]
    Keywords : ADP-ribosylation; Kinases; PARP16; Phosphorylation; UPR biochemistry; Biochemistry; Chemistry;

    Abstract : PARP16/ARTD15 is an intracellular mono-ADP-ribosyltransferase that catalyzes auto- and heteromodification by transfer of a single ADP-ribose moiety. It belongs to the ADP-ribosyltransferase (ART) superfamily. READ MORE

  3. 2. Determining Protein Conformational Ensembles by Combining Machine Learning and SAXS

    University essay from KTH/Tillämpad fysik

    Author : Samuel Eriksson Lidbrink; [2023]
    Keywords : AlphaFold; AlphaFold2; SAXS; protein conformational ensembles; machine learning; protein conformations; reweighting; SAXS; AlphaFold; AlphaFold2; proteinkonformationsensembler; maskininlärning; proteinkonformationer; omviktning;

    Abstract : In structural biology, immense effort has been put into discovering functionally relevant atomic resolution protein structures. Still, most experimental, computational and machine learning-based methods alone struggle to capture all the functionally relevant states of many proteins without very involved and system-specific techniques. READ MORE

  4. 3. Knowledge Distillation of DNABERT for Prediction of Genomic Elements

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Joana Palés Huix; [2022]
    Keywords : Knowledge distillation; Transformers; BERT; Genomics; Promoter identification; Explainability;

    Abstract : Understanding the information encoded in the human genome and the influence of each part of the DNA sequence is a fundamental problem of our society that can be key to unveil the mechanism of common diseases. With the latest technological developments in the genomics field, many research institutes have the tools to collect massive amounts of genomic data. READ MORE

  5. 4. Competition between Phase Separation and Micellization in a Coarse-Grained Protein Model with Two Components

    University essay from Lunds universitet/Institutionen för astronomi och teoretisk fysik - Genomgår omorganisation; Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation

    Author : Fangxuan Lyu; [2022]
    Keywords : Physics and Astronomy;

    Abstract : Intrinsically disordered proteins (IDPs) are widely believed to play a key role in the for- mation of intracellular biomolecular condensates through liquid-liquid phase separation (LLPS). Furthermore, it has been shown in vitro that several IDPs are able to phase sepa- rate on their own. READ MORE

  6. 5. Hybrid Variational Autoencoder for Clustering of Single-Cell RNA-seq Data : Introducing HybridVI, a Variational Autoencoder with two Latent Spaces

    University essay from KTH/Skolan för elektroteknik och datavetenskap (EECS)

    Author : Sarah Narrowe Danielsson; [2022]
    Keywords : Bioinformatics; scRNAseq; Variational Autoencoder; Single-Cell Analysis; Bioinformatik; scRNAseq; Variational Autoencoder; individuell cellanalys;

    Abstract : Single-cell analysis means to analyze cells on an individual level. This individual analysis enhances the investigation of the heterogeneity among and the classification of individual cells. Single-cell analysis is a broad term and can include various measurements. READ MORE