Essays about: "genomics"

Showing result 6 - 10 of 59 essays containing the word genomics.

  1. 6. Image-Based Classification Solutions for Robust Automated Molecular Biology Labs

    University essay from KTH/Medicinteknik och hälsosystem

    Author : Arnold Teo; [2023]
    Keywords : Neural networks; Deep learning; Transfer learning; TensorFlow; Single-cell genomics; Image classification; Neurala nätverk; Djupinlärning; Överförd inlärning; TensorFlow; Enskild cellgenomik; Bildklassificering;

    Abstract : Single-cell genomics (SCG) are methods for investigating heterogeneity between biological cells, among these is Smart-seq which sequences from RNA molecules. A more recent version of this method is Smart-seq3xpress which is currently in the process of being automated by the Sandberg lab at Karolinska Institutet. READ MORE

  3. 7. Single-cell RNA-seq mapping of chicken leukocytes : An investigation into single-cell transcriptomics as an alternative to traditional immunological methods within non-traditional model organisms

    University essay from Uppsala universitet/Mikrobiologi och immunologi

    Author : Matilda Maxwell; [2023]
    Keywords : Bioinformatics; scRNA-seq; avian; immunology; Seurat; leukocytes; chicken; gallus gallus; 10x genomics; PCA;

    Abstract : The immune system is a complex infrastructure where many cells interact with each other and perform duties depending on their type and function. When using traditional immunological methods in studying non-traditional model organisms, such as birds, challenges arise. READ MORE

  4. 8. Detecting structural variants in the DNA of the inbred Scandinavian wolf

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Lars Huson; [2023]
    Keywords : animal; animal population; bioinformatics; biological sciences; biology; Canis lupus; CNV; conservation genetics; conservation genomics; copy-number variation; DNA; endangered population; endangered species; evolution; evolutionary biology; extinction; genetic diversity; genetics; genetic variation; genomes; genomics; grey wolf; inbreeding; inbreeding depression; indel; mutation; pedigree; population genetics; population genomics; Scandinavia; smoove; snakemake; structural variant; SV; wolf; wolves;

    Abstract : Only 40 years ago, just three individuals made the journey from Finland/Russia to found the current wolf population in the southwest of Sweden. This population, that to this date descends from less than 10 founders, has a substantial increased extinction risk due to inbreeding. READ MORE

  5. 9. A recipe for fish and SNPs : Filling the blanks for conservation genomics of Swedish wels catfish (Silurus glanis) populations

    University essay from Uppsala universitet/Institutionen för ekologi och genetik; Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Lars Littmann; [2022]
    Keywords : Catfish; Silurus glanis; Genomics; Genetics; Conservation; Mitochondrial; Whole-genome; NGS; Sweden;

    Abstract : Swedish populations of Wels catfish (Silurus glanis) experienced severe declines during the 19th and 20th centuries. The main causes for the decline were loss of suitable spawning habitat and fragmentation of populations. Currently, three native and two reintroduced populations remain in Sweden. READ MORE

  6. 10. Knowledge Distillation of DNABERT for Prediction of Genomic Elements

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Joana Palés Huix; [2022]
    Keywords : Knowledge distillation; Transformers; BERT; Genomics; Promoter identification; Explainability;

    Abstract : Understanding the information encoded in the human genome and the influence of each part of the DNA sequence is a fundamental problem of our society that can be key to unveil the mechanism of common diseases. With the latest technological developments in the genomics field, many research institutes have the tools to collect massive amounts of genomic data. READ MORE