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Showing result 1 - 5 of 90 essays matching the above criteria.

  1. 1. Systematic Multi-Parametric Analysis of Acute Myeloid Leukemia (AML) Flow Cytometry Drug Screens using Flowty

    University essay from Lunds universitet/Teknisk mikrobiologi

    Author : Augusta Jensen; [2023]
    Keywords : Acute myeloid leukemia; AML; cellular subpopulations; data analysis; precision medicine; Flowty; applied microbiology; Biology and Life Sciences;

    Abstract : Acute myeloid leukemia (AML) is a heterogeneous disease, making it difficult to treat. The standard treatment is intensive chemotherapy and has not changed in 40 years. However, recently new drugs and as less intensive treatment regimens have been approved in the US and in Europe. However. READ MORE

  3. 2. CRISPR Screen to Identify Genes Regulating Melanoma Cell Invasiveness

    University essay from KTH/Proteinvetenskap

    Author : Emma Kroon; [2023]
    Keywords : CRISPR-Cas9; gene knockout; viral packaging; transduction; invasionstest; CRISPR-Cas9; genknockout; viruspackning; transduction; invasion assay;

    Abstract : Maligna cancerceller har förmågan att sprida sig okontrollerat i kroppen och metastasera till avlägsna organ. Kritiskt i metastaserings processen är cancercellers förmåga att invadera närliggande vävnader innan de sprider sig vidare ut i kroppen. READ MORE

  4. 3. Combining doxorubicin and gemcitabine with targeted drugs as a treatment option for high-risk neuroblastoma

    University essay from KTH/Proteinvetenskap

    Author : Alexandra Johannesson; [2023]
    Keywords : neuroblastoma; doxorubicin; gemcitabine; targeted drugs; ATM; neuroblastom; doxorubicin; gemcitabin; målinriktade läkemedel; ATM;

    Abstract : Neuroblastom är en barncancer som uppstår ur det sympatiska nervsystemet och drabbar omkring 15 barn i Sverige varje år. Högriskvarianten är associerad med mycket hög dödlighet och risk för återfall, vilket tros ha att göra med att tumörernas ovanligt heterogena sammansättning tillåter resistenta subpopulationer att motstå konventionella behandlingsmetoder. READ MORE

  5. 4. Understanding the effects of TCP-25 and EDTA interaction : A study of the biophysical aspects of a naturally derived peptide formulation with EDTA for topical application

    University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)

    Author : Ebba Kant; [2023]
    Keywords : chronic wounds; EDTA; biophysical aspects; formulation; pharmaceutical technology; Thrombin derived C-terminal peptide; Technology and Engineering;

    Abstract : Chronic wounds are an emerging healthcare issue and current methods of healing chronic wounds address bacteria but are ineffective against resistant bacteria and the biofilm formation commonly observed in these wounds. Antimicrobial peptides (AMPs) derived from the endogenous wound healing system have been shown to combat bacterial infections, exhibit immunomodulatory effects, as well as improving wound healing. READ MORE

  6. 5. Acoustic Focusing of Lysozyme Crystals

    University essay from KTH/Tillämpad fysik

    Author : Måns Junestrand; [2023]
    Keywords : Protein Crystals; Lysozyme Crystals; Ultrasound; Acoustic Focusing; SFX; Biomedical Physics; Proteinkristaller; Ultraljud; Lysozymkristaller; Akustisk fokusering; SFX; Biomedicinsk fysik;

    Abstract : Acoustic focusing of microscale protein crystals with acoustophoresis technology could reduce clogs during experiments with the scientific technique serial femtosecond x-ray crystallography (SFX). SFX determines molecular structures of proteins, these structures are valuable in drug discovery and fundamental biomedical research. READ MORE