Essays about: "Antibody purification"

Showing result 1 - 5 of 14 essays containing the words Antibody purification.

1. 1. Small Scale Monoclonal Antibody Purification Platform

   University essay from Lunds universitet/Kemiteknik (CI)

   Author : Eric Nielsen; [2022]
   Keywords : PURIFICATION; MONOCLONAL ANTIBODIES; ÄKTA PURE; ÄKTA XPRESS; Chemistry;

   Abstract : The aim of this project is to transfer and implement a monoclonal antibody purification process that is traditionally done on an ÄKTAxpress to another machine called the ÄKTA pure. This is due to the fact that the ÄKTAxpress is being discontinued by the manufacturer and a replace-ment machine is needed for the time being. READ MORE

3. 2. A high-throughput method for screening of protein binding behavior of multimodal anionic exchange ligands

   University essay from Uppsala universitet/Analytisk farmaceutisk kemi

   Author : Ani Avedis; [2021]
   Keywords : Multimodal chromatography; multimodal anionic exchange ligands; product development; purification process; biological drugs; resins;

   Abstract : The biopharmaceutical industry is constantly developing biological drugs, resulting in increased levels of product related impurities having similar characteristics as the target. The aim of the ligand project was to address future challenging purifications by developing new ligands for future resins for the biopharmaceutical industry. READ MORE

4. 3. Advanced control of chromatography systems for automated analysis of monoclonal antibodies

   University essay from Lunds universitet/Kemiteknik (CI)

   Author : Jerry Guan; [2021]
   Keywords : Chemical engineering; Kemiteknik; Chromatography; Analysis; HPLC; Python; Automatic process control; Monoclonal Antibodies; Antibody purification; Technology and Engineering;

   Abstract : Nedströmsprocesser för rening av biologiska läkemedel som monoklona antikroppar rör sig från batch-processer till kontinuerliga, och vidare till helt automatiska, kontinuerliga nedströmsprocsser. En del av visionen för automatiska reningsprocesser är möjligheten att automatiskt analysera från olika steg av reningen. READ MORE

5. 4. The future of viral vectors for gene therapy

   University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

   Author : Elias Ekstedt; Inna Fryckstedt; Hanna Hyllander; Josefin Jonsson; Elin Ring; Felix Wærn; [2021]
   Keywords : Gene therapy; adenovirus; alpharetrovirus; baculovirus; adeno-associated virus; lentivirus; herpes simplex virus; foamy virus; gammaretrovirus;

   Abstract : Gene therapy is a fast growing technology that offers treatments for genetic diseases. The method is based on introducing genetic material into a patient to replace the disease-causing gene, using a vector. READ MORE

6. 5. CUSTOMIZED QUANTIFICATION OF HOST CELL PROTEIN WITH BIO-LAYER INTERFEROMETRY

   University essay from Lunds universitet/Teknisk mikrobiologi

   Author : Eva Sjöblom; [2020]
   Keywords : BLI; HCP; CHO; yeast; host cell protein; bio-layer interferometry; immunoassays; quantification; chinese hamster ovary; ELISA; applied microbiology; teknisk mikrobiologi; Biology and Life Sciences; Technology and Engineering;

   Abstract : Host cell protein (HCP) is quantified in the purification steps of biopharmaceutical production and is part of ensuring the purity of the final drug product. The gold standard method for HCP quantification is enzyme-linked immunosorbent assay (ELISA), but a new approach is proposed here with fully customized bio-layer interferometry assays for yeast and chinese hamster ovary (CHO) cells. READ MORE