Advanced search
Found 3 essays matching the above criteria.
-
1. Metabolic Modelling of Differential Drug Response to Proteasome Inhibitors in Glioblastoma Multiforme
University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskapAbstract : This project was built upon a previous study (Johansson et al.2020) that tested multiple drugs on glioblastoma cell lines and found a big division between the drug response for proteasome inhibitors. READ MORE
-
2. Reconstruction of Genome-Scale Metabolic Models with Concomitant Constraint-Based Modelling for Flux Prediction – a Case Study of Syngas Consuming Hydrogenophaga pseudoflava
University essay from Lunds universitet/Teknisk mikrobiologiAbstract : Metabolic modelling coupled with flux-balance analysis (FBA) has become a popular tool in systems biology for quantitative predictions of metabolic processes in silico, and as an aid in metabolic engineering. Drawing upon gene-protein-reaction associations deducible from information on the genome-level, so-called genome-scale metabolic models (GEMs) are unequalled in their scope as they attempt to encapsulate the entire reactome of a species or cell type. READ MORE
-
3. Utilization of cancer-specific genome-scale metabolic models in pancreatic ductal adenocarcinomas for biomarkers discovery and patient stratification
University essay from Högskolan i Skövde/Institutionen för biovetenskapAbstract : Pancreatic Ductal Adenocarcinomas initiates in the exocrine part of the pancreatic tissue and represents over 90% of all the pancreatic cancers. Pancreatic Ductal Adenocarcinomas are extremely aggressive and are one of the most lethal malignant neoplasms. The five-year relative survival is currently less than 8% of the patients. READ MORE