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Showing result 11 - 15 of 467 essays matching the above criteria.

1. 11. Ovary spheroid formation and quality assessment using two different protocols

   University essay from KTH/Proteinvetenskap

   Author : Nikki Wallius Hiltunen; [2023]
   Keywords : ovary; fertility; spheroid; Biosilk™; three-layer gradient system; äggstock; fertilitet; sfäroid; Biosilk™; trelagers gradientsystem;

   Abstract : Redan innan födseln fastställs kvinnors fertilitet, som karakteriseras av ett begränsat antal äggblåsor, så kallade folliklar. Beståndet av folliklar minskar naturligt med åldern, samtidigt som kvinnors fertilitet beror på deras steroid- och äggproduktion. READ MORE

3. 12. Approved medicinal products with potential companion diagnostic tests : An Inventory of the Swedish/European drug market

   University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

   Author : Katrin Andersson; [2023]
   Keywords : CDx; Companion Diagnostic; IVDMD; In-vitro diagnostic medical devices; Regulation EU 2017 746;

   Abstract : The newly introduced regulation (EU) 2017/746 aims to make In Vitro Diagnostic Medical Devices (IVDMD), which include companion diagnostic tests (CDx), a widespread method of authorising medicinal products in the European market. However, European SmPCs (Summary of Product Characteristics) currently do not explicitly refer to the term or classify tests associated with medicinal products as CDx. READ MORE

4. 13. Computational prediction of cell-cell interactions in the brain-tumour microenvironment

   University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

   Author : Paula Camargo Romera; [2023]
   Keywords : Cancer; Glioblastoma; Computational Biology; Bioinformatics; Microenvironment; Brain tumour; Interactions; Systems Biology;

   Abstract : Glioblastoma is the fastest-growing, and the most common malignant brain tumour in adults. It is normally treated with surgery and radio- or chemotherapy, but the approximate life expectancy is of 15 months with a high probability of cancer recurring. Therefore, there is a need for decreasing its severity. READ MORE

5. 14. Design, production and in vitro evaluation of brain shuttle scFc-scFv8D3 affinity-mutants

   University essay from Uppsala universitet/Institutionen för farmaci

   Author : Jonathan Efverström; [2023]
   Keywords : Blood-brain barrier; In-Cell BBB-trans assay; mTfR1; Transferrin receptor; scFc-scFv8D3; Blod-hjärn barriären; mTfR1; Transferrin receptorn; scFc-scFv8D3;

   Abstract : The blood brain barrier (BBB) is a challenge when developing monoclonal antibodies for neurological diseases as antibodies do not cross the BBB making brain distribution challenging. An antibody construct which binds mTfR1 to pass the BBB, scFc-scFv8D3, have previously been developed. READ MORE

6. 15. Validation of Simultaneous T1 and T2 Mapping Using Cardiac Magnetic Resonance Fingerprinting in Self-Constructed Phantoms : An Analysis of the Reproducibility and Accuracy

   University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

   Author : Sasithon Meesan; [2023]
   Keywords : Cardiac Magnetic Resonance Fingerprinting cMRF ; Cardiac Magnetic Resonance Imaging CMR ; Simultaneous T1 and T2 Mapping; Validation; Accuracy; Reproducibility; Cardiac Magnetic Resonance Fingerprinting cMRF ; Kardiovaskulär Magnetresonans CMR ; Simultant T1 och T2 Parametrisk-Karaktärisering; Validering; Noggrannhet; Reproducerbarhet;

   Abstract : Quantitative cardiac magnetic resonance imaging (CMR) has gained traction within both the clinical and research field due to high prevalence of cardiovascular diseases. Cardiac magnetic resonance fingerprinting (cMRF) is a novel approach introduced to address the limitation associated with evaluation of multiparametric quantitative CMR. READ MORE