Essays about: "Signaling Pathways"

Showing result 1 - 5 of 45 essays containing the words Signaling Pathways.

  1. 1. Hormonal Influence on the Proliferation Potential of C17.2 Neuronal Progenitor Cells

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Alexander Mangano; [2024]
    Keywords : ;

    Abstract : The brain is arguably the most complex organ of the body: Controlling muscles, maintaining homeostasis, processing information. It has the longest developmental period of any organ, and hormones are essential during its development. READ MORE

  3. 2. Ligand-stimulated cleavage of PDGFR-beta

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Agni Karolina Tsiatsiou; [2023]
    Keywords : ;

    Abstract : Platelet-derived growth factor receptors (α and β) are included in the family of receptor tyrosine kinases (RTKs). The dimeric PDGF ligands bind to the PDGF receptors and this results in receptor dimerization, autophosphorylation, and thus activation. The autophosphorylated receptor dimer activates numerous signaling pathways. READ MORE

  4. 3. Investigating ERβ chromatin binding and its potential interaction with LRH-1 in an ovarian context

    University essay from KTH/Proteinvetenskap

    Author : Mick Phenphak; [2023]
    Keywords : estrogen receptor beta; ovary; granulosa cells; ChIP; qPCR; östrogen receptor beta; äggstock; granulosa celler; ChIP; qPCR;

    Abstract : Invasiv äggstockscancer anses vara en av de mest dödligaste gynekologiska maligniteterna. Granulosacelltumör i äggstocken är en sällsynt subtyp av äggstockstumör, som utgör 1–5% av alla äggstockstumörer. De kan kännetecknas av den långsamma tillväxthastigheten och produktionen av höga östrogennivåer. READ MORE

  5. 4. Constructing and analyzing a gene-gene interaction network to identify driver modules in lung cancer using a clustering method

    University essay from Stockholms universitet/Institutionen för data- och systemvetenskap

    Author : Marcell Szalai; [2023]
    Keywords : Lung Cancer; Driver Modules; Artificial Intelligence; Clustering; Gene-Gene Interaction Network; Signaling Pathways;

    Abstract : Cancer is a complex disease with diverse genetic changes that pose significant treatment challenges due to its heterogeneity. Identifying driver modules, which are crucial for cancer progression, has been aided by artificial intelligence (AI) techniques. However, existing approaches lack specificity, particularly for cancer types like lung cancer. READ MORE

  6. 5. Predicting Biomarkers/ Candidate Genes involved in iALL, using Rough Sets based Interpretable Machine Learning Model.

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Girish Pulinkala; [2023]
    Keywords : Machine Learning; Cancer; Oncology; Acute Lymphoblastic Leukemia; Rough sets; Pathway analysis; Feature selection; Bioinformatics; Computational Biology.;

    Abstract : Acute lymphoblastic leukemia is a hematological malignancy that gains a proliferative advantage and originates in the bone marrow. One of the more common genetic alterations in ALL is KMT2A-rearrangement which constitutes 80% of the cases of ALL in infants. READ MORE