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Found 3 essays matching the above criteria.

  1. 1. Development of ultra-sensitive immunoassay on Gyrolab microfluidic platform using Binding Oligo Ladder Detection : Enhancing Gyrolab biomarker assays using Exazym®

    University essay from Uppsala universitet/Institutionen för farmaci

    Author : Sam Vadi Dris; [2024]
    Keywords : Immnoassay; Gyrolab; TNF-alpha; Ultra-sensitive; Cavidi; Exazym; BOLD amplification; Amplification;

    Abstract : Immunoassays are widely used for detection of antigens in a wide range of applications including assays in pharmaceutical development. Immunoassays are continuously improved in many aspects including automatization, miniaturization and extending the dynamic range. READ MORE

  3. 2. Detection and quantification of post-translational modifications in non-invasive samples : Phosphoproteins as biomarkers and a market analysis of protein quantification technologies

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Sammi Baudin; Hillevi Fjellström; Aron Kraft; Erica Lamberg; Måns Rosenbaum; Hanna Sjöstrand; [2023]
    Keywords : Phorphorylation; Proteomics; Biomarkers; Phosphoproteins; PTM; Amyotrophic lateral sclerosis; ALS; Alzheimer s disease; Parkinson s disease; Cancer; xMAP; SIMOA; NULISA; PEA; ELISA; Mass spectrometry; SomaScan;

    Abstract : Post-translational modifications (PTMs) of proteins can be a sign and/or cause of disease. These modified proteins have the potential to be used as biomarkers for diagnostic purposes. However, research in the field is limited. READ MORE

  4. 3. Tau phosphorylation on threonine 217 as a potential biomarker for neurodegenerative diseases

    University essay from Högskolan i Borås/Akademin för textil, teknik och ekonomi

    Author : Sukri Omar Jama; [2019]
    Keywords : P217; hyperphosphorylation; Taupathies; CSF; plasma; serum; Simoa; antibodies; assay; Progressive supranuclear palsy; Alzheimer’s disease and Global glial Taupathies; P217; hyperfosforyrlering; Taupathies; CSF; plasma; serum; Simoa; antikroppar; analys; Progressiv supranukleär pares; Corticobasal degeneration och Globular glialtauopati;

    Abstract : Hyperfosforylering av biomarkörproteinet Tau förekommer i flera neurodegenerativa sjukdomar som kallas Taupathies. Proteinets huvudfunktion i människokroppen är att modulera flexibilitet och stabilitet för axonal-mikrotubulin. I Taupathies utlöser hyperfosforyleringen av Tau instabilitet och neurodegenerationen. READ MORE