Essays about: "TATA box"

Found 1 essay containing the words TATA box.

  1. 1. IRINOTECANTOXICITY RELATED TO GILBERT´S SYNDROME   - COMPARISON OF THREE METHODS FOR GENOTYPING OF UGT1A1 (TA)n

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Lena Fredriksson; [2009]
    Keywords : Fragment analysis; genetic analysis; Gilbert´s syndrome; irinotecan; TATA box; UDP Glucuronosyl-transferase 1A1; UGT1A1 *28;

    Abstract : Gilbert’s syndrome (GS) occurs in approximately 10% of the European population. The most common cause is homozygosity for UGT1A1*28, which is a TA repeat expansion in the promoter of UGT1A1. It is characterised by intermittent hyperbilirubinemia due to reduced hepatic activity of the  enzyme UDP-glucuronosyl-transferase 1A1(UGT1A1). READ MORE