Essays about: "UTR"

Showing result 1 - 5 of 11 essays containing the word UTR.

1. 1. Supervised Learning for Prediction of Tumour Mutational Burden

   University essay from KTH/Matematisk statistik

   Author : Joanna Hargell; [2021]
   Keywords : Supervised Learning; Tumour Mutational Burden; Generalized Linear Models; Decision trees; Support Vector Machines; statistik; tillämpad matematik; statistisk inlärning; mutationsbörda;

   Abstract : Tumour Mutational Burden is a promising biomarker to predict response to immunotherapy. In this thesis, statistical methods of supervised learning were used to predict TMB: GLM, Decision Trees and SVM. READ MORE

3. 2. Increased expression of therapeutic proteins by identification of 3'-UTRs from high expressing genes in CHO cells

   University essay from Linköpings universitet/Institutionen för fysik, kemi och biologi

   Author : Alexander Westlund; [2019]
   Keywords : Mammalian cell; CHO; E. coli; protein expression; plasmid; transformation; Fc-fusion protein; flow cytometry; FACS; transfection; mRNA; UTR; gene engineering;

   Abstract : Therapeutic proteins, a.k.a. biopharmaceuticals, are most commonly produced in expression systems derived from Chinese Hamstery Ovary (CHO) cells, thanks to great capacity of post-translational modifications like secretation, folding and glycosylation. READ MORE

4. 3. Method for tracking orthogonal ribosomes in vivo using MS2coat protein

   University essay from Uppsala universitet/Molekylärbiologi

   Author : John Lindström; [2019]
   Keywords : ;

   Abstract : Ribosomes are large macromolecules responsible for protein synthesisand they consist of both RNA and proteins. Each ribosome is made of one large and one small subunit. Even though the ribosome is one of the most studied machineries in the cell there is a gap in our understanding of how this macromolecule functions in vivo. READ MORE

5. 4. Evaluation of 5´- and 3´-UTR Translation Enhancing Sequences to Improve Translation of Proteins in CHO Cells

   University essay from Linköpings universitet/Teknisk biologi

   Author : Ellen Einarsson; [2018]
   Keywords : Regulation; Untranslated regions; 5´ UTR; 3´ UTR; mRNA; Expression; Flow cytometry;

   Abstract : The purpose of this project was to identify and evaluate nucleotide sequences enhancing translation of proteins in Chinese hamster ovary (CHO) cells. Candidate sequences were placed in the 5´-untranslated region (UTR) or 3´ UTR respectively and evaluated in a CHO-based expression system with a fluorescent Fc-fusion protein as a model protein. READ MORE

6. 5. En väv av former : en redogörelse över förvandlingen av Krokshallstorget från parkering till torg

   University essay from SLU/Dept. of Landscape Architecture, Planning and Management (from 130101)

   Author : Rebecca Wårfors; [2016]
   Keywords : analys; process; yta; plats; rum; genus loci; form; Borås; Krokhallstorget;

   Abstract : Mitt arbete syftar till att skapa ett gestaltningsförslag för en nyanläggning av Krokshallstorget i staden Borås. Det har varit viktigt för mig att ge mig själv tid att analysera platsen grundligt och att noga följa min egen arbetsprocess, vilket tydligt framgår i mitt arbete. READ MORE