Essays about: "gene knockout"

Showing result 11 - 15 of 23 essays containing the words gene knockout.

  1. 11. Inflammasome : Investigating the effect of NEK7 in the activation of the NLRP3 Inflammasome

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Cosmas Adindu Uzowuru; [2020]
    Keywords : NLRP3 inflammasome; NEK7 protein; THP-1; Prime; activate; differentiate; stimulate; cytokines; Interleukin-1 Beta; Interleukin-18;

    Abstract : Inflammation is a biological defence mechanism applied by living organisms against foreign invaders. In the response to DAMPs and PAMPs, organisms use inflammatory multi-protein complexes to fight the attackers. The most studied inflammasome proteins are NLRP3, ASC and Caspase-1. READ MORE

  3. 12. Unravelingthe molecular mechanism behind metabolic reprogramming caused by alterations of the enzyme PI3-kinase

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Angana Heet Patel; [2019]
    Keywords : ;

    Abstract : Oncogenes and tumor suppressor genes play a key role in cancer induction and progression. They directly or indirectly regulate critical metabolic pathways, phosphatidylinositol-3 kinase pathway being frequently activated pathway in cancer. READ MORE

  4. 13. The effect of DLG knockout, vitamin D and probiotic treatment on Drosophila gene expression

    University essay from Högskolan i Skövde/Institutionen för hälsa och lärande

    Author : Sophie Améen; [2018]
    Keywords : DLG; Drosophila melanogaster; Vitamin D; Probiotics; Colorectal cancer;

    Abstract : Background: Colorectal cancer is one of the most frequently diagnosed cancers today. Dlg is a tumor suppressor gene commonly silenced in cancer cells. Many colorectal cancer patients are subject to vitamin D3 deficiency and/ or an altered microbiome. READ MORE

  5. 14. Interactions of Streptococcus equi and Mast Cells: In the Search of Virulence Factors

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Christopher von Beek; [2018]
    Keywords : Streptococcus equi; Streptococcus; mast cells; infection; streptolysin; SLS;

    Abstract : Mast cells are key players of the innate immune system due to their location at the interface of host and pathogen encounters, such as on mucosal surfaces or the skin. Secreting a variety of compounds, they communicate with other immune cells in a highly specific manner. READ MORE

  6. 15. Unfolding the role of Ire1 and DNAJB1 in Parkinson’s disease

    University essay from Lunds universitet/Examensarbeten i molekylärbiologi

    Author : Emma Källstig; [2017]
    Keywords : Biology and Life Sciences;

    Abstract : Parkinson’s disease (PD) is a movement disorder of the brain which is hallmarked by the presence of large protein-rich cytoplasmic aggregates, called Lewy bodies (LBs), in the neurons. The protein α-synuclein (α-syn) is abundant in these aggregates, and can itself form aggregates. READ MORE