Essays about: "myeloid"

Showing result 1 - 5 of 22 essays containing the word myeloid.

1. 1. Systematic Multi-Parametric Analysis of Acute Myeloid Leukemia (AML) Flow Cytometry Drug Screens using Flowty

   University essay from Lunds universitet/Teknisk mikrobiologi

   Author : Augusta Jensen; [2023]
   Keywords : Acute myeloid leukemia; AML; cellular subpopulations; data analysis; precision medicine; Flowty; applied microbiology; Biology and Life Sciences;

   Abstract : Acute myeloid leukemia (AML) is a heterogeneous disease, making it difficult to treat. The standard treatment is intensive chemotherapy and has not changed in 40 years. However, recently new drugs and as less intensive treatment regimens have been approved in the US and in Europe. However. READ MORE

3. 2. Comparing dropout regularization algorithms for convolutional neural networks identifying malignant cells for diagnosis of leukemia

   University essay from Uppsala universitet/Statistiska institutionen

   Author : Hampus Engström; Alexander Koutakis; [2023]
   Keywords : classification; Bernoulli; Gaussian; spatial; machine learning; cancer; myeloid; myeloproliferative neoplasms;

   Abstract : Fast and high quality classifications of cells inflicted with malignant mutations is essential for diagnosing patients with different forms of leukemia, to quickly be able give patients the crucial care they need. Convolutional neural networks (CNNs) can be trained and used for this purpose. READ MORE

4. 3. Phenotype and function of imiquimod-treated MUTZ-3 derived Langerhans cells in potential psoriatic 3D skin model

   University essay from Malmö universitet/Institutionen för biomedicinsk vetenskap (BMV)

   Author : Emilie Allentoft Schousboe; [2023]
   Keywords : 3D models; imiquimod; Langerhans cells; MUTZ-3 cell line; pro-inflammatory cytokines; psoriasis;

   Abstract : Upon encounter of an antigen, epidermis-resident Langerhans cells (LCs) become activated and present the processed antigen to T cells of the draining lymph nodes, resulting in tolerogenic or inflammatory responses. In psoriasis plaques, skin homeostasis is disrupted and replaced by an inflammatory dermatitis. READ MORE

5. 4. An Application of Cluster Analysis in Identifying and Evaluating Prognostic Subgroups for Therapy-Related Acute Myeloid Leukemia

   University essay from Uppsala universitet/Statistiska institutionen

   Author : Stefanie Antonilli; [2022]
   Keywords : AML; lymphoma; heterogeneous data; cluster analysis; k-prototypes algorithm;

   Abstract : Treatment for lymphoma with alkylating therapy is known to increase the risk of secondary malignancies such as Acute Myeloid Leukemia (AML), although the risk is not fully understood. This study investigates the characteristics of AML that arise after lymphoma treatment in contrastto AML cases without a prior lymphoma. READ MORE

6. 5. Understanding the pathophysiology ofrecurrent UBTF mutations associated withpediatric AML

   University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

   Author : Annie Paulsson; [2022]
   Keywords : Hematologi; Cancer; AML; UBTF; leukemi;

   Abstract : Acute myeloid leukaemia (AML) is highly heterogeneous haematological malignancy, which represents a challenge in the understanding of the disease. Relapse in AML is common, andmany relapsed patients respond poorly to conventional treatment, leading to a low survivalrate. READ MORE