Essays about: "nya läkemedel"

Showing result 16 - 20 of 90 essays containing the words nya läkemedel.

  1. 16. Combination of Antimetabolites with Chemotherapy as a Novel Treatment Option in High-risk Neuroblastoma

    University essay from KTH/Proteinvetenskap

    Author : Maja Lundström; [2022]
    Keywords : cell cycle arrest; chemotherapy resistance; combination therapy; cytarabine; doxorubicin; gemcitabine;

    Abstract : 20 svenska barn diagnostiseras årligen med barntumören neuroblastom (NB). Läkemedelsresistens och intratumoral heterogenitet försvårar behandlingen och 50-60% av hög-risk NB-patienter drabbas av återfall. Subpopulationer av resistenta celler har identifierats i hög-risk NB-cellinjer, vilket belyser behovet av nya behandlingsalternativ. READ MORE

  3. 17. Design improvements for an Organ-on-chip system : Implementation and evaluation of a bubble trap

    University essay from Uppsala universitet/Institutionen för materialvetenskap

    Author : Albin Jonasson; Linnéa Soto Carlsson; [2022]
    Keywords : Organ-on-chip; Microfluidics; Lab-on-chip; Lab-on-a-chip; bubble trap; epithelial; endothelial; cells; biomedical engineering; chip; TEER; Mikrofluidik; labb-på-chip; organ-på-chip; medicinsk teknik; medicinteknik; TEER; bubbelfälla; epitelceller; endotelceller;

    Abstract : The field of organ-on-chip is a relatively new area of research and builds upon the principle of engineering microfluidic systems to mimic the body’s internal environment as precisely as possible. Eventually these models could hopefully simulate whole organ-systems and enable the examination of the cell’s or organ’s reaction to foreign substances like new pharmaceuticals in a better way than current models. READ MORE

  4. 18. Quality and Regulatory Issues Related to Continuous Manufacturing of Biologics

    University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)

    Author : Sorosh Ziarati; [2022]
    Keywords : Continuous Manufacturing; Regulation; Continuous freeze drying; Biopharmaceutical; Trastuzumab; Pharmaceutical Technology; Technology and Engineering;

    Abstract : Introduction: Continuous Manufacturing involves the continuous feeding of input materials into the transformation of in-process materials within, and the concomitant removal of output materials from a manufacturing process based on ICH guideline. In these systems, all the processes from raw material to final finished product would be continuously produced. READ MORE

  5. 19. Optimization of immunotherapeutic relevant ABD-derived affinity proteins for prolonged serum half-life

    University essay from KTH/Proteinvetenskap

    Author : Ebba Bergström; [2022]
    Keywords : Half-Life extension; Human serum Albumin HSA ; Interleukin 17c IL17c ; ABD-Derived Affinity ProTeins ADAPT ; Protein-based drugs.;

    Abstract : Marknaden för proteinbaserade läkemedel, de så kallade biologiska läkemedlen, är idag en industri som omsätter miljarder. Ett vanligt sätt att utveckla dessa läkemedel på är med hjälp av monoklonala antikroppar då de kan binda till sitt mål med hög specificitet. READ MORE

  6. 20. The importance of the two- and three component systems WalRK and VraTSR for antibiotic resistance and phage susceptibility in Staphylococcus aureus

    University essay from Lunds universitet/Teknisk mikrobiologi

    Author : Jack Abrahamsson; [2022]
    Keywords : MRSA; Vancomycin; VISA; phage; bacteriophage; Staphylococcus aureus; antibiotic resistance; chemical engineering; Biology and Life Sciences;

    Abstract : Staphylococcus aureus is a human commensal bacterium, living primarily on the skin and in the nose. It is also a pathogen able to cause a wide range of diseases, including food poisoning, infection of wounds but also more serious infections such as bacteremia and endocarditis. READ MORE