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Showing result 1 - 5 of 7 essays matching the above criteria.

  1. 1. Detecting structural variants in the DNA of the inbred Scandinavian wolf

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Lars Huson; [2023]
    Keywords : animal; animal population; bioinformatics; biological sciences; biology; Canis lupus; CNV; conservation genetics; conservation genomics; copy-number variation; DNA; endangered population; endangered species; evolution; evolutionary biology; extinction; genetic diversity; genetics; genetic variation; genomes; genomics; grey wolf; inbreeding; inbreeding depression; indel; mutation; pedigree; population genetics; population genomics; Scandinavia; smoove; snakemake; structural variant; SV; wolf; wolves;

    Abstract : Only 40 years ago, just three individuals made the journey from Finland/Russia to found the current wolf population in the southwest of Sweden. This population, that to this date descends from less than 10 founders, has a substantial increased extinction risk due to inbreeding. READ MORE

  3. 2. The relative contribution of CNVs and SNPs to local adaptation in Norway spruce (Picea abies)

    University essay from Uppsala universitet/Växtekologi och evolution; Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Yuxuan Niu; [2022]
    Keywords : CNVs; SNPs; Norway spruce; local adaptation;

    Abstract : In the current environment of severe climate change, studying the adaptability of Norway spruce to the environment, that is, local adaptation is of great significance for helping to protect forest tree species and genetic breeding. As a structural variation, copy number variations (CNVs) have been proved to play an important role in shaping population structure and local adaptation in marine species, going beyond traditional studies focusing only on SNPs. READ MORE

  4. 3. Antibiotic-Regulated Plasmid Copy Number Variation: A Driver of Antibiotic Resistance?

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Ahmed Eldek; [2019]
    Keywords : antibiotic resistance; plasmid copy number; ddPCR;

    Abstract : Plasmids are small circular DNA molecules within bacterial cells that are separated from the bacterial chromosome and replicate independently. Also, they play a crucial role in the dissemination of antibiotic resistance genes among bacteria through horizontal gene transfer. READ MORE

  5. 4. Karakterisering av genetiska riskfaktorer för dilaterad kardiomyopati hos hund

    University essay from SLU/Dept. of Animal Breeding and Genetics

    Author : Sofia Jankulovska; [2017]
    Keywords : dilaterad kardiomyopati; hund; grand danois; newfoundlandshundar; genetisk associationsstudie; next-generation sequencing; digitalPCR; genetiska riskfaktorer; dilated cardiomyopathy; canine; grand danois; Newfoundlands dogs; genome-wide association studies; next-generation sequencing; digitalPCR; genetic risk factors;

    Abstract : Dilaterad kardiomyopati (DCM), är en hjärtsjukdom som förekommer hos ett flertal hundraser. Etiologin är inte fastställd. Genetiska studier på hund visar att gener involverade i utvecklandet av DCM skiljer sig åt mellan olika hundraser. READ MORE

  6. 5. Seasonal variation in fungal biomass : the effects of soil temperature and moisture in a boreal forest

    University essay from SLU/Dept. of Forest Mycology and Plant Pathology

    Author : Malin Leidefors; [2016]
    Keywords : fungi; biomass; qPCR; temperature; moisture; climate;

    Abstract : Climate change involves a series of events promoted by elevated levels of atmospheric CO2, such as increased temperature and changes in seasonal precipitation patterns, soil temperature, moisture and nutrient availability. Soils in boreal forests are often well-drained and not underlain by permafrost, which makes boreal forests susceptible to droughts. READ MORE