Essays about: "Crohn s Disease"

Showing result 1 - 5 of 6 essays containing the words Crohn s Disease.

  1. 1. Metagenomic analysis of Crohn’s Disease

    University essay from Uppsala universitet/Molekylär epidemiologi

    Author : Gustav Lennemyr Ahlström; [2022]
    Keywords : Metagenomics; Machine Learning; Microbiome; IBD; Human Health; AI; Crohn s Disease; Shotgun Sequencing Data; Data Analysis; Bioinformatics; MetaPhlAn3; Supervised ML; Mikrobiom; Crohn s Sjukdom; Bioinformatik;

    Abstract : Inflammatory Bowel Disease (IBD) is a chronic and incurable condition that is increasing inprevalence across the globe. This illness consist of two forms: Crohn’s Disease (CD) andUlcerative Colitis (UC). CD is characterised by a patch inflammation pattern across the gut anda multitude of different factors, such as diet. READ MORE

  3. 2. Bridging inflammatory bowel diseases and hepatobiliary disorders through pathway enrichment and module-based approach

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Alaa Saloum; [2020]
    Keywords : ;

    Abstract : Inflammatory bowel diseases (IBD) including Crohn’s disease (CD) and ulcerative colitis (UC) are associated with various hepatobiliary disorders. Two of the chronic hepatobiliary disorders that may coexist with inflammatory bowel diseases are: primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC). READ MORE

  4. 3. The comparative efficacy of biologics in patients with Crohn´s disease and Ulcerative Colitis

    University essay from Örebro universitet/Institutionen för medicinska vetenskaper

    Author : Elan Adel Khalaf; [2019]
    Keywords : IBD; Chron´s disease; Ulcerative Colitis; biologics; remission.;

    Abstract : Introduction The fundamental concept for modern inflammatory bowel disease (IBD) treatment algorithm is an early induction of mucosal healing and its maintenance. Biological therapies are becoming mainstays of IBD therapy. READ MORE

  5. 4. Evaluating the biological relevance of disease consensus modules : An in silico study of IBD pathology using a bioinformatics approach

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Joel Ströbaek; [2019]
    Keywords : Bioinformatics; Disease module; Consensus module; Disease consensus module; Network medicine; Inflammatory bowel disease; Crohn s disease; Ulcerative colitis; S2B; NSC; Tetralith; MODifieR;

    Abstract : Inflammatory bowel disease encompasses a variety of heterogeneous chronic inflammatory diseases that affect the gastrointestinal tract, where Crohn’s disease and ulcerative colitis are the principal examples. The etiology of these, and many other complex human diseases, remain largely unknown and therefore pose relevant targets for novel research strategies. READ MORE

  6. 5. Biophysical characterization of the *5 protein variant of human thiopurine methyltransferase by NMR spectroscopy

    University essay from Molekylär Bioteknik

    Author : Robert Gustafsson; [2012]
    Keywords : thiopurine methyltransferase; hydrogen exchange; nuclear magnetic resonance; relaxation; protein dynamics; local stability;

    Abstract : Human thiopurine methyltransferase (TPMT) is an enzyme involved in the metabolism of thiopurine drugs, which are widely used in leukemia and inflammatory bowel diseases such as ulcerative colitis and Crohn´s disease. Due to genetic polymorphisms, approximately 30 protein variants are present in the population, some of which have significantly lowered activity. READ MORE