Essays about: "methyltransferase"

Showing result 1 - 5 of 7 essays containing the word methyltransferase.

  1. 1. Establishment and Characterisation of new Immunoreagents for diagnosis of Ovarian cancer

    University essay from

    Author : Fanny Carlsson; [2023-04-19T12:15:23Z 2023-04-19T12:15:23Z 2022 2023]
    Keywords : ovarian; cancer; monoclonal; antibodies; biomarkers; CARM1; PARPi; EZH2i;

    Abstract : Ovarian cancer is the most lethal of all gynaecological cancers and it is often diagnosedat an advanced stage due to diffuse and only mild symptoms at early stages.Early detection is crucial to increase survival but high-grade serous ovarian cancer(HGSOC) often presents non-specific symptoms, such as loss of appetite, bloating ofabdomen and tiredness. READ MORE

  3. 2. Impact of SETD2 mutation in the regulation of Autophagy in Clear Cell Renal Cell Carcinoma Cells

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Hanzhao Zhang; [2018]
    Keywords : ;

    Abstract : Background: Autophagy is an important cellular pathway in cell growth and maintenance, during which unnecessary organelles and materials in cells can be degraded. Regulation of autophagy is related to tumorigenesis. READ MORE

  4. 3. Gene expression patterns in Fraxinus excelsior clones with contrasting susceptibility to Hymenoscyphus fraxineus

    University essay from SLU/Dept. of Forest Mycology and Plant Pathology

    Author : Shadi Eshghi Sahraei; [2016]
    Keywords : Hymenoscyphus fraxinus; Fraxinus excelsior; ABA8H; RNA-seq; ATAF1;

    Abstract : This study aimed at investigating gene expression patterns in resistant and susceptible clones of Fraxinus excelsior L. (European ash) in response to infection with Hymenoscyphus fraxineus. A further objective of this study was to investigate the role of ABA8-hydroxylase genes (ABA8H) in European ash under infection with H. fraxineus. READ MORE

  5. 4. Are Restriction Enzymes Recognition Sites Underrepresented in the Organisms That Host Them?

    University essay from Lunds universitet/Examensarbeten i bioinformatik

    Author : Dina Gamaleldin Mansour Aly; [2016]
    Keywords : Biology and Life Sciences;

    Abstract : The restriction modification enzyme system is a vital bacterial defense system against invading phages. Restriction modification system consists of a restriction enzyme and a methyltransferase enzyme that work in a complementary fashion to cut foreign DNA and at the same time methylates and protects host DNA. READ MORE

  6. 5. In vitro studies of Thiopurine S-Methyltransferase: Ligand binding interactions and development of a new enzymatic activity assay for TPMTwt, TPMT*6 and TPMT*8

    University essay from Linköpings universitet/Institutionen för fysik, kemi och biologi; Linköpings universitet/Tekniska fakulteten

    Author : Lovisa Hemmingsson; Johan Klasén; [2015]
    Keywords : Thiopurine S-Methyltransferase; 6-mercaptourine; methotrexate; isothermal titration calorimetry; fluorescence spectroscopy;

    Abstract : Acute lymphoblastic leukemia, one of the most malignant cancer forms in children is commonly treated with the thiopurine 6-mercaptopurine (6-MP) in combination with a high dose of methotrexate (MTX). 6-Mercaptopurine is in the body metabolized by the enzyme thiopurine S-methyltransferase (TPMT). READ MORE