Essays about: "monoclonal antibodies in immunohistochemistry"

Found 5 essays containing the words monoclonal antibodies in immunohistochemistry.

  1. 1. Establishment and Characterisation of new Immunoreagents for diagnosis of Ovarian cancer

    University essay from

    Author : Fanny Carlsson; [2023-04-19T12:15:23Z 2023-04-19T12:15:23Z 2022 2023]
    Keywords : ovarian; cancer; monoclonal; antibodies; biomarkers; CARM1; PARPi; EZH2i;

    Abstract : Ovarian cancer is the most lethal of all gynaecological cancers and it is often diagnosedat an advanced stage due to diffuse and only mild symptoms at early stages.Early detection is crucial to increase survival but high-grade serous ovarian cancer(HGSOC) often presents non-specific symptoms, such as loss of appetite, bloating ofabdomen and tiredness. READ MORE

  3. 2. Can the selective PDGF-receptor antagonist STI571 reduce hypoxia in solid tumors, and enhance drug uptake of Taxol, by lowering the interstitial fluid pressure in stroma rich breast carcinoma, BT-474

    University essay from Linnéuniversitetet/Institutionen för kemi och biomedicin (KOB)

    Author : Marcus Runeson; [2015]
    Keywords : ;

    Abstract : Background Solid tumors have high interstitial fluid pressure, IFP. This cause a dramatic loss in uptake of anti cancer drugs with poor clinical outcome as result. Treatment with PDGF-receptor antagonist STI-571 lowers tumor IFP and enhances uptake of small compounds. READ MORE

  4. 3. Semi-automated immunohistochemical staining of the VEGF-A-protein for clinical use and the identification in NHG-graded breast carcinoma

    University essay from Uppsala universitet/Institutionen för kvinnors och barns hälsa

    Author : Engla Maria Helena Sedin; [2014]
    Keywords : CD31; grade; immunohistochemistry; invasive breast cancer; vascular endothelial growth factors;

    Abstract : Angiogenesis has a crucial influence on tumour development and identification of microvessels in malignant breast cancer tissue is an indicator for worse prognosis. Angiogenesis is partially governed by the family of vascular endothelial growth factors (VEGF) and their receptors, by which the VEGF-A-protein seems to be the most important factor. READ MORE

  5. 4. Analysis of tumour infiltrating leukocytes in colon cancer carcinoma in a syngeneic rat model

    University essay from Institutionen för fysik, kemi och biologi

    Author : Annelie Borgström; [2010]
    Keywords : Tumour infiltrating leukocytes; Immunohistochemistry; Colon cancer; monoclonal antibodies; BR96 antibody;

    Abstract : Tumour immunity is a balance between immune mediators that promote tumor progression versus mediators that promote tumor rejection. Infiltrating lymphocytes in human colorectal cancer tissues are independent prognostic factors for a better survival and a high number of cytotoxic CD8+ T-cells have been associated with a better prognosis in terms of a longer and disease free survival for the patient. READ MORE

  6. 5. THE EXPRESSION OF THROMBOMODULIN, TISSUE FACTOR, TISSUE FACTOR PATHWAY INHIBITOR AND ENDOTHELIAL PROTEIN C RECEPTOR IN NORMAL AND IUGR PLACENTA

    University essay from Institutionen för medicinsk biokemi och mikrobiologi

    Author : Tina Källebring; [2005]
    Keywords : THROMBOMODULIN; TISSUE FACTOR; ENDOTHELIAL PROTEIN C RECEPTOR; IUGR; PLACENTA;

    Abstract : The aim of this study was to examine the expression of Thrombomodulin, Tissue Factor, Tissue Factor Pathway Inhibitor and Endothelial Protein C Receptor in placenta throughout the three phases of the third trimester in the normal placenta and in IUGR placenta from full term. Twenty-five normal placenta samples and twenty-five IUGR placenta samples were obtained and each sample was stained by immunohistochemistry using monoclonal antibodies. READ MORE