Essays about: "Fusion Protein"

Showing result 11 - 15 of 40 essays containing the words Fusion Protein.

  1. 11. Design, production and evaluation of cross linked target proteins to an affibody-based carrier framework aimed for affinity protein: antigen structure determination using single particle Cryo-EM

    University essay from KTH/Proteinvetenskap

    Author : Richard Brunsell; [2021]
    Keywords : Cryo-EM; Structure determination; Protein A; Affibody; Aldolase; Scaffold; Rigid helix fusion; Photoconjugation; UV crosslinking; BPA;

    Abstract : Small proteins are difficult to study at high resolution with single-particle cryo-electron microscopy (cryo-EM). In general, sample properties such as large size (> 80 kDa), symmetry and rigidity are key to utilize this technology. READ MORE

  3. 12. Characterization of the fusion protein mNG-Aβ1-42 as a fluorescence reporter probe for amyloid structure

    University essay from Linköpings universitet/Institutionen för fysik, kemi och biologi

    Author : Linnéa Fredén; [2020]
    Keywords : Alzheimer’s Disease AD ; Amyloids; Aβ; fusion protein; mNeonGreen; mNG-Aβ1-42; Crystallization; mouse brain tissue; human brain tissue; amyloid fluorescent probes;

    Abstract : Alzheimer’s Disease, also called AD, is a horrible, degenerative brain disease that more than 35 million people over the world have. Today, there is no cure for this disease, only treatments that are temporarily relieving the symptoms. The two proteins that is thought to be the main cause of AD is amyloid β (Aβ) and tau. READ MORE

  4. 13. Development of an antibioticsresistancebased method fordirected evolution of proteases

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Vilma Lagebro; [2020]
    Keywords : Protease engineering; protease; directed evolution; TEVp; Amyloid beta; CAT;

    Abstract : Proteases have a fundamental role in regulating diverse biological processes and are important in the biotechnological and medical fields. Therapeutic proteases have great potential but have been limited due to the lack of high throughput protein engineering methods. READ MORE

  5. 14. Genetic code expansion and dCas9-DAXXHBD as synthetic routes for epigenome editing

    University essay from Högskolan i Skövde/Institutionen för hälsovetenskaper

    Author : Michael Schrempf; [2020]
    Keywords : ;

    Abstract : Epigenome editing has become a promising new tool to study the effects of singular histone modifications on the transcriptional activity of mammalian cells. Although many different approaches have been developed during the recent years many approaches used dCas9 fused epigenetic effector proteins to deposit the epigenetic mark at target sites. READ MORE

  6. 15. Construction of a fusion protein for anchoring the inflammatory receptor NLRP3 to the cell membrane

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Rebecca Ling; [2019]
    Keywords : NLRP3 inflammasome; Overlap PCR; Fusion Protein; LPI™ technology;

    Abstract : The innate immune system are a cooperation of many components – receptors being one of them. Both membrane-bound and cytosolic receptors play a large role in the defence system against pathogens and danger. READ MORE