Essays about: "breast cancer resistance protein"

Showing result 1 - 5 of 7 essays containing the words breast cancer resistance protein.

  1. 1. Dietary fibres and dairy products : How does it affect the development of cancer and diabetes type 2

    University essay from SLU/Department of Molecular Sciences

    Author : Elin Forslund; [2021]
    Keywords : Dietary fibers; Dairy products; Cancer; Diabetes;

    Abstract : Eating habits are one of the main factors that can affect the development of non-communicable diseases such as cancer and diabetes. The prevention of cancer and diabetes is a significant public health challenge due to the growing rate all over the world. Dietary behaviours are one of the important factors to lower the risk of these diseases. READ MORE

  3. 2. In silico and in vitro determination of substrate specificity for Breast Cancer Resistance Protein (BCRP) transporter at the blood-brain barrier

    University essay from Uppsala universitet/Institutionen för farmaci

    Author : Fen Wang; [2021]
    Keywords : BCRP; substrate specificity; BBB; ATP-binding cassette ABC transporter; Drug transport;

    Abstract : Background The Breast Cancer Resistance Protein (BCRP) drug transporter is important for drug disposition and plays a critical role in regulating drug entry into the brain. Its substrate spectrum overlaps with substrates of Multi Drug Resistance Protein 1 (MDR1, P-gp), which influences and complicates the interpretation of data on drug distribution into tissues (e. READ MORE

  4. 3. Intratumoral heterogeneity in early breast cancer

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : MARIA STOGIANNITSI; [2020]
    Keywords : breast cancer; RNAscope technique; heterogeneity of BC; RNA in situ hybridization;

    Abstract : The use of adjuvant The use of adjuvant polychemotherapy (ACT) confers unequivocal benefits in terms of relapse free (RFS) and overall survival (OS) after resection of early breast cancer (BC). Although the magnitude of benefit is the same regardless of clinicopathological factors such as ER expression or nodal stage, it is clear that a substantial proportion of patients will eventually relapse and succumb to the disease. READ MORE

  5. 4. The impact of CRISPR/Cas9 generated mutations in pioneer transcription factors FOXA1 and GATA3 on oestrogen receptor function

    University essay from Lunds universitet/Examensarbeten i molekylärbiologi

    Author : Miroslav Bobrik; [2018]
    Keywords : Biology and Life Sciences;

    Abstract : Breast cancer is the most common cancer among women and two thirds of all breast cancers are classified as oestrogen receptor positive. ER is a transcription factor that regulates gene expression and promote cell proliferation that is critical in mammary gland development, and its aberrant activity is commonly present in breast cancer. READ MORE

  6. 5. Effekten av sulforafan på genuttrycket av breast cancer resistance protein i MCF-7 celler

    University essay from SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Author : Karolina Sjöberg; [2015]
    Keywords : sulforafan; breast cancer resistance protein; BCRP; nuclear factor E2-related factor-2; Nrf2; MCF-7; bröstcancerceller; mjölk; sulforaphane; breast cancer resistance protein; breast cancer cells; milk;

    Abstract : Sulforafan är en isothiocyanat-förening som finns i stora mängder i olika kålväxter. Sulforafan har setts ha en kemopreventiv inverkan bland annat genom att inducera fas II-enzymer styrda av transkriptionsfaktorn nuclear factor E2-related factor-2 (Nrf2). READ MORE