Essays about: "genome sequencing"
Showing result 1 - 5 of 134 essays containing the words genome sequencing.
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1. Multiple-Emitter Super-resolution Imaging using the Alternating Descent Conditional Gradient Method
University essay from Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation; Lunds universitet/Institutionen för astronomi och teoretisk fysik - Genomgår omorganisationAbstract : This thesis examines the state-of-the-art 2D super-resolution technique alternating descent conditional gradient (ADCG) method's ability to accurately localize fluorophores in diffraction-limited single molecule images (SMI) and analyze the impact of pre-processing and post-processing modules on ADCG's fluorophore localization. A synthetic dataset obtained from the 2013 Grand Challenge localization microscopy and a temporally linked dataset obtained from an unpublished set of Optical DNA mapping experiments performed by Jonathan Jeffet at the NanoBioPhotonix Lab at Tel-Aviv University were initially segmented to extract their noise parameters. READ MORE
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2. Establishing novel approaches for assessing safety of genome-editing-based therapeutics
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : Genome editing based medicines are a new therapeutic modality being developed. They show great promise for a spectrum of genetic diseases lacking conventional treatment strategies. A major obstacle that prevents such therapies to reach the clinic is their safety. READ MORE
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3. Exploring the genetic cause of myotonic dystrophy in horses
University essay from SLU/Dept. of Animal Breeding and GeneticsAbstract : Myotonic Dystrophy (MD) is an inherited neuromuscular disorder that leads to a wide range of clinical signs including stiffness, abnormal muscle relaxation, and muscle atrophy or hypertrophy. Affected muscles develop a prolonged contracture in response to percussion of the muscle and show waxing and waning complex repetitive discharges in electromyography (EMG). READ MORE
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4. The gut microbiome and nausea in pregnancy
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : Nausea and vomiting are among the most common symptoms of early pregnancy. Its most extreme form Hyperemesis gravidarum often requires hospitalization and has been linked as a risk factor of perinatal depression. READ MORE
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5. SubKluster: Novel method to bin scaffolds from cereal genomes into subgenomes using substring frequency analysis
University essay from Lunds universitet/Examensarbeten i bioinformatikAbstract : The genome of the Belinda variety of the hexaploid oat (Avena sativa) has recently been sequenced and assembled. This project aims to improve the assembly by clustering the thousands of scaffolds into their three ancestral subgenomes using Principle Component Analysis (PCA) of kmer and repeat-element frequencies. READ MORE
