Essays about: "pharmacokinetics"

Showing result 21 - 25 of 43 essays containing the word pharmacokinetics.

  1. 21. Tidsförlopp för plasmakoncentrationen av bensylpenicillin efter intramuskulär administration av bensylpenicillin med tillsats av lidokain med adrenalin till häst

    University essay from SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Author : Judith Grossman; [2016]
    Keywords : bensylpenicillin; penicillin G; häst; intramuskulär administration; lidokain; adrenalin; farmakokinetik; PK PD; benzylpenicillin; penicillin G; horse; intramuscular administration; lidocaine; adrenaline; pharmacokinetics;

    Abstract : Penicillin är den mest använda antibiotikan inom svensk veterinärmedicin. Det är ett väl beprövat och säkert läkemedel som jämfört med många andra antibiotika har en mer begränsad benägenhet att selektera fram resistenta bakterier. READ MORE

  3. 22. Forming the protein corona on nanoparticles

    University essay from Lunds universitet/Examensarbeten i molekylärbiologi

    Author : Charley Lemland; [2016]
    Keywords : Biology and Life Sciences;

    Abstract : Nanomedicine is a growing field with great potential. When nanoparticles (NPs) come in contact with biological fluids a protein corona is formed on the surface. The protein corona has an effect on the pharmacokinetics and biological response. READ MORE

  4. 23. Plasmakoncentration-tidsprofilen av bensylpenicillin efter intramuskulär administration av bensylpenicillinprokain till häst

    University essay from SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Author : Amelie Lind; [2016]
    Keywords : bensylpenicillinprokain; prokain; bensylpenicillin; Penovet; häst; plasmakoncentration; farmakokinetik; dos; penicillinchock; prokaintoxicitet; procaine penicillin G; procaine; benzylpenicillin; plasma concentration-time profile; horse; plasma concentration; pharmacokinetics; dose; penicillin; shock; procaine toxicity;

    Abstract : Bensylpenicillin är den mest använda antibiotikan inom svensk veterinärmedicin. Aktiviteten är god mot många vanliga grampositiva bakterier och ringa mot de flesta gramnegativa bakterier. READ MORE

  5. 24. Bayesian parameter estimation in Ecolego using an adaptive Metropolis-Hastings-within-Gibbs algorithm

    University essay from Uppsala universitet/Institutionen för informationsteknologi

    Author : Sverrir Þorgeirsson; [2016]
    Keywords : ;

    Abstract : Ecolego is scientific software that can be used to model diverse systems within fields such as radioecology and pharmacokinetics. The purpose of this research is to develop an algorithm for estimating the probability density functions of unknown parameters of Ecolego models. READ MORE

  6. 25. Individualization of fixed-dose combination regimens : Methodology and application to pediatric tuberculosis

    University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Author : Gunnar Yngman; [2015]
    Keywords : pharmacometrics; pharmacokinetics; PK; population pharmacokinetics; optimal design; FDC; fixed-dose combination; pediatrics; tuberculosis; rifampicin; pyrazinamide; isoniazid; ethambutol; modeling; simulation; estimation; allometric scaling; stochastical simulation and estimation; NONMEM; MATLAB; FO; FOCE; Expectation-Maximization algorithm; importance sampling; Nelder-Mead method; logistic function; discontinuity; euclidean distance; Sammon mapping; global minimum; local minima;

    Abstract : Introduction: No Fixed-Dose Combination (FDC) formulations currently exist for pediatric tuberculosis (TB) treatment. Earlier work implemented, in the software NONMEM, a rational method for optimizing design and individualization of pediatric anti-TB FDC formulations based on patient body weight, but issues with parameter estimation, dosage strata heterogeneity and representative pharmacokinetics remained. READ MORE