Essays about: "Two-component regulatory system"

Found 2 essays containing the words Two-component regulatory system.

  1. 1. The importance of the two- and three component systems WalRK and VraTSR for antibiotic resistance and phage susceptibility in Staphylococcus aureus

    University essay from Lunds universitet/Teknisk mikrobiologi

    Author : Jack Abrahamsson; [2022]
    Keywords : MRSA; Vancomycin; VISA; phage; bacteriophage; Staphylococcus aureus; antibiotic resistance; chemical engineering; Biology and Life Sciences;

    Abstract : Staphylococcus aureus is a human commensal bacterium, living primarily on the skin and in the nose. It is also a pathogen able to cause a wide range of diseases, including food poisoning, infection of wounds but also more serious infections such as bacteremia and endocarditis. READ MORE

  3. 2. Searching for novel protein-protein specificities using a combined approach of sequence co-evolution and local structural equilibration

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Olle Nordesjö; [2016]
    Keywords : Biotechnology; Bioinformatics; Molecular Structure; Protein Conformation; Computing Methodologies; Protein-protein interaction; Binding affinity; Mutation analysis; Amino acid mutation; in-silico binding affinity prediction; Two-component regulatory system; Histidine Kinase; Response Regulator; Prediction; PhoQ; PhoP; Phosphatase;

    Abstract : Greater understanding of how we can use protein simulations and statistical characteristics of biomolecular interfaces as proxies for biological function will make manifest major advances in protein engineering. Here we show how to use calculated change in binding affinity and coevolutionary scores to predict the functional effect of mutations in the interface between a Histidine Kinase and a Response Regulator. READ MORE